After Homer pollutes the town's water supply, Springfield is encased in a gigantic dome by the EPA and the Simpsons are declared fugitives.
The Simpsons Movie
Marge Simpson / Selma Bouvier / Patty Bouvier (voice)
Bart Simpson / Maggie Simpson / Ralph / Nelson / Todd Flanders / TV Daughter / Woman on Phone (voice)
Lisa Simpson (voice)
Scratchy / Mr. Burns / Rev. Lovejoy / Ned Flanders / Lenny / Skull / President Arnold Schwarzenegger / Kent Brockman / Principal Skinner / Dr. Hibbert / Smithers / Toll Booth Man / Guard / Otto / Kang (voice)
Milhouse Van Houten / Jimbo Jones / Rod Flanders (voice)
Sweet Old Lady / Colin / Mrs. Skinner / Nelson's Mother / Pig / Cat Lady / Female EPA Worker / G.P.S. Woman / Cookie Kwan / Lindsey Naegle / TV Son / Medicine Woman / Girl on Phone (voice)
Russ Cargill (voice)
Man / EPA Driver (voice)
Edna Krabappel (voice)
Martin Prince (voice)
Helen Lovejoy (voice)
TV Dad (voice)
Billie Joe Armstrong (voice)
Mike Dirnt (voice)
Tre Cool (voice)
Fat Tony (voice)
Tom Hanks (voice)
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